Extra Super Vidalista 100 mg is a combination medication that contains:
- Tadalafil 40 mg
- Dapoxetine 60 mg
It is marketed to treat both erectile dysfunction (ED) and premature ejaculation (PE) in the same tablet.
Here’s how each ingredient works:
1. Tadalafil 40 mg (for erectile dysfunction)
Tadalafil belongs to a class of medicines called PDE5 inhibitors.
How it works:
- Sexual stimulation causes the release of nitric oxide in the penis.
- This increases a chemical called cGMP, which relaxes smooth muscle and widens blood vessels.
- Tadalafil blocks the enzyme (PDE5) that breaks down cGMP.
- As a result, blood flow to the penis increases, making it easier to achieve and maintain an erection.
Important points:
- It does not automatically cause an erection. Sexual arousal is still required.
- Effects typically begin within 30–60 minutes.
- The effect can last up to 36 hours, although this doesn’t mean you’ll have an erection the entire time—just that erections are easier to achieve during that window.
2. Dapoxetine 60 mg (for premature ejaculation)
Dapoxetine is a short-acting SSRI that is taken only when needed.
How it works:
- It increases serotonin levels in parts of the brain involved in ejaculation.
- Higher serotonin activity delays the ejaculation reflex.
- This helps increase the time before ejaculation and may improve control.
It is usually taken 1–3 hours before sexual activity.
Is 40 mg of tadalafil a high dose?
Yes.
The usual tadalafil doses for ED are:
- 10 mg as needed (common starting dose)
- 20 mg as the maximum recommended as-needed dose
- 2.5–5 mg daily for once-daily therapy
A 40 mg dose is twice the standard maximum recommended dose for ED. Combination products containing 40 mg tadalafil are sold in some countries or online, but they are not approved in many major regulatory jurisdictions for routine ED treatment. The higher dose may increase the risk of side effects without clearly improving effectiveness for most men.
Possible side effects
Tadalafil:
- Headache
- Flushing
- Nasal congestion
- Indigestion
- Muscle or back pain
- Dizziness
- Rarely, prolonged erection (lasting more than 4 hours), sudden vision loss, or sudden hearing loss—these require immediate medical attention.
Dapoxetine:
- Nausea
- Dizziness
- Headache
- Diarrhea
- Dry mouth
- Insomnia
- Fainting can occur, particularly when standing up quickly.
Important precautions
Do not take this medication if you:
- Use nitrate medications (such as nitroglycerin), because combining them with tadalafil can cause a dangerous drop in blood pressure.
- Have certain serious heart conditions or have been advised to avoid sexual activity.
- Are taking certain antidepressants, monoamine oxidase inhibitors (MAOIs), or some medications that strongly interact with dapoxetine, unless a clinician has confirmed the combination is safe.
If you’re considering using Extra Super Vidalista, it’s worth discussing whether a standard tadalafil dose (10–20 mg), with or without separate treatment for premature ejaculation, might be a safer and equally effective option. If you have any heart disease, low blood pressure, or take other medications, a healthcare professional should review it before use.




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